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Research Progress on Glycolytic Reprogramming and Lactylation Crosstalk in Tumors

Metabolic reprogramming is a hallmark of cancer, with the Warburg effect-driven aerobic glycolysis leading to a substantial accumulation of lactate in the tumor microenvironment. For a long time, lactate was considered a mere metabolic end product; however, recent studies have found that it acts as...

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Main Authors: Yilin FENG, Ying SUN, Xu HAO, Huitong YANG, Anqi LU, Yuan LIU, Jinchan XIA, Long FENG, Min JIANG, Xiru ZHAO
Format: Artigo
Language:Chinês
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2026-01-01
Series:Chinese Journal of Lung Cancer
Subjects:
lactylation
glycolytic reprogramming
tumor microenvironment
immune evasion
targeted therapy
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2026.101.02
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