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The role of the C2A domain of synaptotagmin 1 in asynchronous neurotransmitter release.

Following nerve stimulation, there are two distinct phases of Ca2+-dependent neurotransmitter release: a fast, synchronous release phase, and a prolonged, asynchronous release phase. Each of these phases is tightly regulated and mediated by distinct mechanisms. Synaptotagmin 1 is the major Ca2+ sens...

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Autori principali: Mallory C Shields, Matthew R Bowers, Hannah L Kramer, McKenzie M Fulcer, Lara C Perinet, Marissa J Metz, Noreen E Reist
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2020-01-01
Serie:PLoS ONE
Accesso online:https://doi.org/10.1371/journal.pone.0232991
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