Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode

Ghrelin is a gastric peptide hormone with important physiological functions, including growth hormone release and appetite-stimulating activity. Here, authors solved the crystal structure of the ghrelin receptor bound to antagonist and suggested a possible mechanism of activation by acyl-modified gh...

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Hlavní autoři:	Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata, Misuzu Tanaka, Kenji Mori, Tomoko Uemura, Takuya Kobayashi, So Iwata, Masayasu Kojima
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2020-08-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-020-17554-1
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!