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Acyl modifications in bovine, porcine, and equine ghrelins

Ghrelin is a peptide hormone with various important physiological functions. The unique feature of ghrelin is its serine 3 acyl-modification, which is essential for ghrelin activity. The major form of ghrelin is modified with n-octanoic acid (C8:0) by ghrelin O-acyltransferase. Various acyl modifica...

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Principais autores: Takanori Ida, Hatsumi Tominaga, Eri Iwamoto, Akito Kurogi, Ayaka Okura, Kengo Shimada, Johji Kato, Atsutoshi Kuwano, Hirotaka Ode, Sayaka Nagata, Kazuo Kitamura, Takashi Yazawa, Miho Sato-Hashimoto, Masahiro Yasuda, Mikiya Miyazato, Yuki Shiimura, Takahiro Sato, Masayasu Kojima
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-05-01
coleção:Frontiers in Endocrinology
Assuntos:
ghrelin
acyl-modification
GHS-R
n-octanoic acid
n-butanoic acid
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2024.1411483/full
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