Functionally selective activation of the dopamine receptor D2 is mirrored by the protein expression profiles
Abstract The development of functionally selective or biased ligands is a promising approach towards drugs with less side effects. Biased ligands for G protein-coupled receptors can selectively induce G protein activation or β-arrestin recruitment. The consequences of this selective action on cellul...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2021-02-01
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| Serija: | Scientific Reports |
| Online dostop: | https://doi.org/10.1038/s41598-021-83038-x |
| Oznake: |
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