Ligand recognition and biased agonism of the D1 dopamine receptor
D1 dopamine receptor is an important drug target for treatment of hypertension and Parkinson’s disease. Here, authors report three cryo-EM structures of the D1R-Gs complex bound to three distinct D1R-selective drugs.
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2022-06-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-022-30929-w |
| Etykiety: |
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