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Immunoglobulins G from Sera of Amyotrophic Lateral Sclerosis Patients Induce Oxidative Stress and Upregulation of Antioxidative System in BV-2 Microglial Cell Line

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with a very fast progression, no diagnostic tool for the presymptomatic phase, and still no effective treatment of the disease. Although ALS affects motor neurons, the overall pathophysiological condition points out to the non-cell...

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Hlavní autoři: Milena Milošević, Katarina Milićević, Iva Božić, Irena Lavrnja, Ivana Stevanović, Dunja Bijelić, Marija Dubaić, Irena Živković, Zorica Stević, Rashid Giniatullin, Pavle Andjus
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017-11-01
Edice:Frontiers in Immunology
Témata:
amyotrophic lateral sclerosis
immunoglobulin G
HyPer
SypHer
oxidative stress
antioxidative system
On-line přístup:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01619/full
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