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Immunoglobulins G from Sera of Amyotrophic Lateral Sclerosis Patients Induce Oxidative Stress and Upregulation of Antioxidative System in BV-2 Microglial Cell Line

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with a very fast progression, no diagnostic tool for the presymptomatic phase, and still no effective treatment of the disease. Although ALS affects motor neurons, the overall pathophysiological condition points out to the non-cell...

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Principais autores: Milena Milošević, Katarina Milićević, Iva Božić, Irena Lavrnja, Ivana Stevanović, Dunja Bijelić, Marija Dubaić, Irena Živković, Zorica Stević, Rashid Giniatullin, Pavle Andjus
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-11-01
coleção:Frontiers in Immunology
Assuntos:
amyotrophic lateral sclerosis
immunoglobulin G
HyPer
SypHer
oxidative stress
antioxidative system
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01619/full
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