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Immunoglobulins G from Sera of Amyotrophic Lateral Sclerosis Patients Induce Oxidative Stress and Upregulation of Antioxidative System in BV-2 Microglial Cell Line

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with a very fast progression, no diagnostic tool for the presymptomatic phase, and still no effective treatment of the disease. Although ALS affects motor neurons, the overall pathophysiological condition points out to the non-cell...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Milena Milošević, Katarina Milićević, Iva Božić, Irena Lavrnja, Ivana Stevanović, Dunja Bijelić, Marija Dubaić, Irena Živković, Zorica Stević, Rashid Giniatullin, Pavle Andjus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017-11-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
amyotrophic lateral sclerosis
immunoglobulin G
HyPer
SypHer
oxidative stress
antioxidative system
Online-Zugang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01619/full
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