A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity.

Recombinant adenoviruses are among the most promising tools for vaccine antigen delivery. Recently, the development of new vectors has focused on serotypes to which the human population is less exposed in order to circumvent pre-existing anti vector immunity. This study describes the derivation of a...

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Principais autores:	Matthew D J Dicks, Alexandra J Spencer, Nick J Edwards, Göran Wadell, Kalifa Bojang, Sarah C Gilbert, Adrian V S Hill, Matthew G Cottingham
格式:	Artigo
语言:	Inglês
出版:	Public Library of Science (PLoS) 2012-01-01
丛编:	PLoS ONE
在线阅读:	https://doi.org/10.1371/journal.pone.0040385
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