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A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity.

Recombinant adenoviruses are among the most promising tools for vaccine antigen delivery. Recently, the development of new vectors has focused on serotypes to which the human population is less exposed in order to circumvent pre-existing anti vector immunity. This study describes the derivation of a...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Matthew D J Dicks, Alexandra J Spencer, Nick J Edwards, Göran Wadell, Kalifa Bojang, Sarah C Gilbert, Adrian V S Hill, Matthew G Cottingham
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science (PLoS) 2012-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:https://doi.org/10.1371/journal.pone.0040385
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