A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells

Neurodegenerative diseases (NDDs) are progressive multifactorial disorders of the nervous system sharing common pathogenic features, including intracellular misfolded protein aggregation, mitochondrial deficit, and inflammation. Taking into consideration the multifaceted nature of NDDs, development...

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Autori principali:	Beatrice Polini, Lorenzo Zallocco, Francesca Gado, Rebecca Ferrisi, Caterina Ricardi, Mariachiara Zuccarini, Vittoria Carnicelli, Clementina Manera, Maurizio Ronci, Antonio Lucacchini, Riccardo Zucchi, Laura Giusti, Grazia Chiellini
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-05-01
Serie:	Cells
Soggetti:	cannabinoid receptor type II (CBR2) autophagy neuroinflammation proteomic β-amyloid TFEB
Accesso online:	https://www.mdpi.com/2073-4409/13/10/875
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