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Taurine attenuates lipid accumulation via the eCB-CB1 axis: evidence from adipose metabolomics in HFD-fed mice and 3D adipocyte spheroids

IntroductionObesity, driven by adipose tissue dysfunction, is a major global health challenge and a key contributor to metabolic disorders. Although taurine shows anti-obesity potential, its precise mechanisms for attenuating adipocyte lipid accumulation remain unclear.MethodsIn this study, high-fat...

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Main Authors: Qingjie Wu, Yuxin Shao, Lin Zhu, Xinzhe Guo, Shengquan Mi, Yanzhen Zhang, Ping Chang, Changying Xie, Junxia Guo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-03-01
Series:Frontiers in Nutrition
Subjects:
cannabinoid receptor type 1
endocannabinoid
lipid accumulation
obesity
taurine
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2026.1782392/full
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