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NAMPT orchestrates fibroblast cuproptosis and immune crosstalk during IPF progression

BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by excessive fibroblast activation and extracellular matrix deposition, leading to severe tissue remodeling and poor prognosis. While current treatments offer limited efficacy. Emerging ev...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Junyu Jiang, Xinghe Liu, Guo Yang, Jia Xie, Weijiao Mou, Yunfei Xiang, Tao Zhang, Wenyu Du, Qingsong Chen, Fating Zhou, Guangbin Huang, Dingyuan Du
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-05-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
cell-cell communication
cuproptosis
idiopathic pulmonary fibrosis
immune crosstalk
multi-omics
NAMPT
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1726692/full
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