NAMPT orchestrates fibroblast cuproptosis and immune crosstalk during IPF progression

BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by excessive fibroblast activation and extracellular matrix deposition, leading to severe tissue remodeling and poor prognosis. While current treatments offer limited efficacy. Emerging ev...

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Autors principals:	Junyu Jiang, Xinghe Liu, Guo Yang, Jia Xie, Weijiao Mou, Yunfei Xiang, Tao Zhang, Wenyu Du, Qingsong Chen, Fating Zhou, Guangbin Huang, Dingyuan Du
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Immunology
Matèries:	cell-cell communication cuproptosis idiopathic pulmonary fibrosis immune crosstalk multi-omics NAMPT
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1726692/full
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