KCa3.1 inhibition-induced activation of the JNK/c-Jun signaling pathway enhances IL-10 expression in peripherally-induced regulatory T cells
The KCa3.1 inhibition up-regulates IL-10 expression in regulatory T (Treg) cells in the recovery phase of inflammatory bowel disease (IBD) model mice; however, the underlying signaling pathway remains unclear. We investigated the involvement of AP-1 (Fos/Jun) and NF-κB in the expression of IL-10 and...
Gardado en:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2022-01-01
|
| Series: | Journal of Pharmacological Sciences |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S1347861321000931 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|