Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators

Summary: Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-transcriptionally by affecting translation and degradation of the target mRNAs upon base-pairing interactions. Here we present a general approach combining imaging and mathematical modeling to determine kineti...

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Detalhes bibliográficos

Principais autores:	Matthew A. Reyer, Shriram Chennakesavalu, Emily M. Heideman, Xiangqian Ma, Magda Bujnowska, Lu Hong, Aaron R. Dinner, Carin K. Vanderpool, Jingyi Fei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-09-01
Colecção:	Cell Reports
Assuntos:	bacterial small RNA gene regulation fluorescence microscopy mathematical modeling
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124721012183
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