Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators

Summary: Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-transcriptionally by affecting translation and degradation of the target mRNAs upon base-pairing interactions. Here we present a general approach combining imaging and mathematical modeling to determine kineti...

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Auteurs principaux:	Matthew A. Reyer, Shriram Chennakesavalu, Emily M. Heideman, Xiangqian Ma, Magda Bujnowska, Lu Hong, Aaron R. Dinner, Carin K. Vanderpool, Jingyi Fei
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2021-09-01
Collection:	Cell Reports
Sujets:	bacterial small RNA gene regulation fluorescence microscopy mathematical modeling
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2211124721012183
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