Induced Pluripotent Stem Cell Generation-Associated Point Mutations Arise during the Initial Stages of the Conversion of These Cells

A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue. In this study, we approached this critical issue in different ways, including an assess...

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Main Authors: Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Masumi Abe
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2014-01-01
סדרה:Stem Cell Reports
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2213671113001318
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