Induced Pluripotent Stem Cell Generation-Associated Point Mutations Arise during the Initial Stages of the Conversion of These Cells

A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue. In this study, we approached this critical issue in different ways, including an assess...

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Huvudupphovsmän: Sugiura, Mayumi, Kasama, Yasuji, Araki, Ryoko, Hoki, Yuko, Sunayama, Misato, Uda, Masahiro, Nakamura, Miki, Ando, Shunsuke, Abe, Masumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916761/
https://ncbi.nlm.nih.gov/pubmed/24511470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.11.006
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