Generation of Genome Integration-free Induced Pluripotent Stem Cells from Fibroblasts of C57BL/6 Mice without c-Myc Transduction

Although the induction of genome integration-free induced pluripotent stem cells (iPSCs) has been reported, c-Myc was still required for the efficient generation of these cells. Herein, we report mouse strain-dependent differences in the c-Myc dependence for iPSC generation and the successful genera...

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Main Authors: Jincho, Yuko, Araki, Ryoko, Hoki, Yuko, Tamura, Chihiro, Nakamura, Miki, Ando, Shunsuke, Kasama, Yasuji, Abe, Masumi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924067/
https://ncbi.nlm.nih.gov/pubmed/20554535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115915
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