Hyperglycemia drives lmmune evasion in colorectal cancer through VISTA stabilization

Abstract Hyperglycemia, the defining feature of diabetes mellitus, enhances cancer immune evasion through multiple mechanisms. V-domain immunoglobulin suppressor of T cell activation (VISTA) overexpression in tumor cells induces CD8⁺ T cell exhaustion, thereby promoting immune evasion. However, whet...

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Xehetasun bibliografikoak

Egile Nagusiak:	Xin Liu, Qian Liu, Dong Guo, Zezhou Zhao, Jing Wang, Yaoxian Xiang, Kangjie Wang, Lijun Yang, Ke Zhu, Li Wang, Ruofan Li, Xu Gao, Chan Zhang, Yurong Cheng, Dong Yan, Yingying Tong
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2026-01-01
Saila:	Cell Communication and Signaling
Gaiak:	Colorectal cancer VISTA USP22 Hyperglycemia Immune evasion Phosphorylation
Sarrera elektronikoa:	https://doi.org/10.1186/s12964-025-02642-w
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