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Does conserved domain SOD1 mutation has any role in ALS severity and therapeutic outcome?

Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with disease pathology. Oxidative stress induced bunina and lewy bodies formation...

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Autors principals: Surinder Pal, Abha Tiwari, Kaushal Sharma, Suresh Kumar Sharma
Format: Artigo
Idioma:Inglês
Publicat: BMC 2020-10-01
Col·lecció:BMC Neuroscience
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Accés en línia:http://link.springer.com/article/10.1186/s12868-020-00591-3
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