Does conserved domain SOD1 mutation has any role in ALS severity and therapeutic outcome?

Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. ALS genetics has identified various genes to be associated with disease pathology. Oxidative stress induced bunina and lewy bodies formation...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Surinder Pal, Abha Tiwari, Kaushal Sharma, Suresh Kumar Sharma
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2020-10-01
Цуврал:	BMC Neuroscience
Нөхцлүүд:	Amyotrophic lateral sclerosis SOD1 PolyPhen2 QMEAN Ramachandran plot PHP-SNP
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12868-020-00591-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!