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Tumor suppression by control of matrix metalloproteinase recycling

Secretion of matrix metalloproteinases (MMPs) enables cancer cells to degrade extracellular matrix, thus promoting tumor invasion and metastasis. We have recently found that the endosomal protein WDFY2 serves as a gatekeeper for MMP recycling from endosomes and that deletion of WDFY2, which is frequ...

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Bibliografski detalji
Glavni autori: Marte Sneeggen, Kay O. Schink, Harald Stenmark
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2019-11-01
Serija:Molecular & Cellular Oncology
Teme:
Online pristup:http://dx.doi.org/10.1080/23723556.2019.1646606
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