Endocytic BDNF secretion regulated by Vamp3 in astrocytes
Abstract Brain-derived neurotrophic factor (BDNF) regulates diverse brain functions via TrkB receptor signaling. Due to the expression of TrkB receptors, astrocytes can internalize extracellular BDNF proteins via receptor-mediated endocytosis. Endocytosed BDNF can be re-secreted upon stimulation, bu...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2021-10-01
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| Edice: | Scientific Reports |
| On-line přístup: | https://doi.org/10.1038/s41598-021-00693-w |
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