Tumor suppression by control of matrix metalloproteinase recycling
Secretion of matrix metalloproteinases (MMPs) enables cancer cells to degrade extracellular matrix, thus promoting tumor invasion and metastasis. We have recently found that the endosomal protein WDFY2 serves as a gatekeeper for MMP recycling from endosomes and that deletion of WDFY2, which is frequ...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis Group
2019-11-01
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| Schriftenreihe: | Molecular & Cellular Oncology |
| Schlagworte: | |
| Online-Zugang: | http://dx.doi.org/10.1080/23723556.2019.1646606 |
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