The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

The biogenesis of 60S ribosomal subunits is initiated in the nucleus where rRNAs and proteins form pre-60S particles. These pre-60S particles mature by transiently interacting with various assembly factors. The ~5000 amino-acid AAA+ ATPase Rea1 (or Midasin) generates force to mechanically remove ass...

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Hlavní autoři:	Piotr Sosnowski, Linas Urnavicius, Andreas Boland, Robert Fagiewicz, Johan Busselez, Gabor Papai, Helgo Schmidt
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2018-11-01
Edice:	eLife
Témata:	Rea1 midasin CryoEM ribosome maturation AAA+ protein molecular machine
On-line přístup:	https://elifesciences.org/articles/39163
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