Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Abstract The transcriptional regulatory network governing the differentiation and functionality of oligodendrocytes (OLs) is essential for the formation and maintenance of the myelin sheath, and hence for the proper function of the nervous system. Perturbations in the intricate interplay of transcri...

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Detalhes bibliográficos

Principais autores:	Gilad Levy, May Rokach, Inbar Fischer, Omri Kimchi-Feldhorn, Shiri Shoob, Ela Bar, Tali Rosenberg, Joanna Bartman, Hadar Parnas, Meitar Grad, Ifat Israel-Elgali, Galit E. Sfadia, Sari S. Trangle, Anna Vainshtein, Yael Eshed Eisenbach, Olaf Jahn, Sophie B. Siems, Hauke B. Werner, Noam Shomron, Yaniv Assaf, Elior Peles, Inna Slutsky, Asaf Marco, Boaz Barak
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-09-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-025-63500-4
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