Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Abstract The transcriptional regulatory network governing the differentiation and functionality of oligodendrocytes (OLs) is essential for the formation and maintenance of the myelin sheath, and hence for the proper function of the nervous system. Perturbations in the intricate interplay of transcri...

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主要な著者:	Gilad Levy, May Rokach, Inbar Fischer, Omri Kimchi-Feldhorn, Shiri Shoob, Ela Bar, Tali Rosenberg, Joanna Bartman, Hadar Parnas, Meitar Grad, Ifat Israel-Elgali, Galit E. Sfadia, Sari S. Trangle, Anna Vainshtein, Yael Eshed Eisenbach, Olaf Jahn, Sophie B. Siems, Hauke B. Werner, Noam Shomron, Yaniv Assaf, Elior Peles, Inna Slutsky, Asaf Marco, Boaz Barak
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-09-01
シリーズ:	Nature Communications
オンライン･アクセス:	https://doi.org/10.1038/s41467-025-63500-4
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