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IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors

Abstract Cells that are exposed to harmful genetic damage, either from internal or external sources, may undergo senescence if they are unable to repair their DNA. Senescence, characterized by a state of irreversible growth arrest, can spread to neighboring cells through a process known as the senes...

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Збережено в:
Бібліографічні деталі
Автори: Nicola Alessio, Domenico Aprile, Gianfranco Peluso, Valeria Mazzone, Deanira Patrone, Giovanni Di Bernardo, Umberto Galderisi
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2024-02-01
Серія:Cell Communication and Signaling
Предмети:
Онлайн доступ:https://doi.org/10.1186/s12964-024-01469-1
Теги: Додати тег
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