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Meta-analysis of senescent cell secretomes to identify common and specific features of the different senescent phenotypes: a tool for developing new senotherapeutics

Abstract DNA damage resulting from genotoxic injury can initiate cellular senescence, a state characterized by alterations in cellular metabolism, lysosomal activity, and the secretion of factors collectively known as the senescence-associated secretory phenotype (SASP). Senescence can have benefici...

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Autors principals: Yo Oguma, Nicola Alessio, Domenico Aprile, Mari Dezawa, Gianfranco Peluso, Giovanni Di Bernardo, Umberto Galderisi
Format: Artigo
Idioma:Inglês
Publicat: BMC 2023-09-01
Col·lecció:Cell Communication and Signaling
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Accés en línia:https://doi.org/10.1186/s12964-023-01280-4
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