Factor inhibiting HIF negatively regulates antiviral innate immunity via hydroxylation of IKKϵ

Summary: Activation of type I interferon (IFN-1) signaling is essential to protect host cells from viral infection. The full spectrum of IFN-I induction requires the activation of a number of cellular factors, including IκB kinase epsilon (IKKϵ). However, the regulation of IKKϵ activation in respons...

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Hlavní autoři:	Xiaolian Cai, Rui Wang, Junji Zhu, Xiong Li, Xing Liu, Gang Ouyang, Jing Wang, Zhi Li, Chunchun Zhu, Hongyan Deng, Wuhan Xiao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-01-01
Edice:	Cell Reports
Témata:	CP: Immunology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124723016182
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