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Factor inhibiting HIF negatively regulates antiviral innate immunity via hydroxylation of IKKϵ

Summary: Activation of type I interferon (IFN-1) signaling is essential to protect host cells from viral infection. The full spectrum of IFN-I induction requires the activation of a number of cellular factors, including IκB kinase epsilon (IKKϵ). However, the regulation of IKKϵ activation in respons...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiaolian Cai, Rui Wang, Junji Zhu, Xiong Li, Xing Liu, Gang Ouyang, Jing Wang, Zhi Li, Chunchun Zhu, Hongyan Deng, Wuhan Xiao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2024-01-01
Rangatū:Cell Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124723016182
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