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Structural Modification Endows Small-Molecular SN38 Derivatives with Multifaceted Functions

As a camptothecin derivative, 7-ethyl-10-hydroxycamptothecin (SN38) combats cancer by inhibiting topoisomerase I. SN38 is one of the most active compounds among camptothecin derivatives. In addition, SN38 is also a theranostic reagent due to its intrinsic fluorescence. However, the poor water solubi...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yi Dai, Meng Qian, Yan Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-06-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1420-3049/28/13/4931
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