Structural Modification Endows Small-Molecular SN38 Derivatives with Multifaceted Functions
As a camptothecin derivative, 7-ethyl-10-hydroxycamptothecin (SN38) combats cancer by inhibiting topoisomerase I. SN38 is one of the most active compounds among camptothecin derivatives. In addition, SN38 is also a theranostic reagent due to its intrinsic fluorescence. However, the poor water solubi...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2023-06-01
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| Schriftenreihe: | Molecules |
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| Online-Zugang: | https://www.mdpi.com/1420-3049/28/13/4931 |
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