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Structural Modification Endows Small-Molecular SN38 Derivatives with Multifaceted Functions

As a camptothecin derivative, 7-ethyl-10-hydroxycamptothecin (SN38) combats cancer by inhibiting topoisomerase I. SN38 is one of the most active compounds among camptothecin derivatives. In addition, SN38 is also a theranostic reagent due to its intrinsic fluorescence. However, the poor water solubi...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Yi Dai, Meng Qian, Yan Li
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: MDPI AG 2023-06-01
Цуврал:Molecules
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/1420-3049/28/13/4931
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