Sexual dimorphism in metabolomic and phenotypic spectra of UGT deficiency: findings from the Canadian Longitudinal Study on Aging

Abstract Background Two of the most frequently deleted genes in the human genome are the UDP-glycosyltransferases UGT2B17 and UGT2B28. They encode metabolic enzymes of the glucuronidation pathway that plays a pivotal role in the maintenance of cellular homeostasis for a variety of small molecule met...

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Principais autores:	Ana Lucia Rivera-Herrera, Michèle Rouleau, Mahukpe Narcisse Ulrich Singbo, Tania Cuppens, Julien Prunier, Arnaud Droit, David Simonyan, Chantal Guillemette
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
coleção:	Biology of Sex Differences
Assuntos:	CLSA Metabolomics Glycosyltransferase Human gene knockout Metabolic disorders
Acesso em linha:	https://doi.org/10.1186/s13293-025-00708-5
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