Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells

ABSTRACT HIV-1 virion production is inefficient in cells derived from mice and other rodents reflecting cell-intrinsic defects to interactions between the HIV-1 auxiliary proteins Tat and Rev and host dependency factors CCNT1 (Cyclin T1) and XPO1 (exportin-1, also known as CRM1), respectively. In hu...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Ryan T. Behrens, Jyothi Krishnaswamy Rajashekar, James W. Bruce, Edward L. Evans, Amelia M. Hansen, Natalia Salazar-Quiroz, Lacy M. Simons, Paul Ahlquist, Judd F. Hultquist, Priti Kumar, Nathan M. Sherer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2023-10-01
Edice:	mBio
Témata:	human immunodeficiency virus lentiviruses transcription nuclear export Cyclin T1 CCNT1
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.00420-23
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!