A comprehensive analysis of the use of nucleoside analogues in RNA therapeutics

Abstract Background mRNA therapeutics represent a promising frontier in the development of vaccines, anti-cancer treatments, and gene replacement therapies. The mRNA platform facilitates the rapid design of effective and safe candidates. However, native mRNA molecules are inherently characterized by...

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主要な著者:	Alisa A. Kukushkina-Zvezdova, Anna A. Zherebtsova, Darya V. Telegina, Ivan A. Skvortsov, Roman A. Ivanov, Vasiliy V. Reshetnikov
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2026-04-01
シリーズ:	Journal of Translational Medicine
主題:	mRNA therapeutics Nucleoside analogues mRNA stability mRNA reactogenicity
オンライン･アクセス:	https://doi.org/10.1186/s12967-026-08083-4
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