Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways

A comparative study of the possibilities of using ribokinase → phosphopentomutase → nucleoside phosphorylase cascades in the synthesis of modified nucleosides was carried out. Recombinant phosphopentomutase from <i>Thermus thermophilus</i> HB27 was obtained for the first time: a strain producing a s...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ilja V. Fateev, Maria A. Kostromina, Yuliya A. Abramchik, Barbara Z. Eletskaya, Olga O. Mikheeva, Dmitry D. Lukoshin, Evgeniy A. Zayats, Maria Ya. Berzina, Elena V. Dorofeeva, Alexander S. Paramonov, Alexey L. Kayushin, Irina D. Konstantinova, Roman S. Esipov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-04-01
coleção:	Biomolecules
Assuntos:	purine nucleoside phosphorylase biocatalysis enzyme cascade expression of recombinant enzymes
Acesso em linha:	https://www.mdpi.com/2218-273X/11/4/586
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!