Synthesis of Substituted 1,2,4-Triazole-3-Thione Nucleosides Using <i>E. coli</i> Purine Nucleoside Phosphorylase

1,2,4-Triazole derivatives have a wide range of biological activities. The most well-known drug that contains 1,2,4-triazole as part of its structure is the nucleoside analogue ribavirin, an antiviral drug. Finding new nucleosides based on 1,2,4-triazole is a topical task. The aim of this study was...

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Egile Nagusiak:	Ilya V. Fateev, Sobirdjan A. Sasmakov, Jaloliddin M. Abdurakhmanov, Abdukhakim A. Ziyaev, Shukhrat Sh. Khasanov, Farkhod B. Eshboev, Oybek N. Ashirov, Valeriya D. Frolova, Barbara Z. Eletskaya, Olga S. Smirnova, Maria Ya. Berzina, Alexandra O. Arnautova, Yulia A. Abramchik, Maria A. Kostromina, Alexey L. Kayushin, Konstantin V. Antonov, Alexander S. Paramonov, Valeria L. Andronova, Georgiy A. Galegov, Roman S. Esipov, Shakhnoz S. Azimova, Anatoly I. Miroshnikov, Irina D. Konstantinova
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2024-06-01
Saila:	Biomolecules
Gaiak:	nucleoside phosphorylases nucleosides ribavirin antiviral activity
Sarrera elektronikoa:	https://www.mdpi.com/2218-273X/14/7/745
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