Synthesis of Substituted 1,2,4-Triazole-3-Thione Nucleosides Using <i>E. coli</i> Purine Nucleoside Phosphorylase

1,2,4-Triazole derivatives have a wide range of biological activities. The most well-known drug that contains 1,2,4-triazole as part of its structure is the nucleoside analogue ribavirin, an antiviral drug. Finding new nucleosides based on 1,2,4-triazole is a topical task. The aim of this study was...

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主要な著者:	Ilya V. Fateev, Sobirdjan A. Sasmakov, Jaloliddin M. Abdurakhmanov, Abdukhakim A. Ziyaev, Shukhrat Sh. Khasanov, Farkhod B. Eshboev, Oybek N. Ashirov, Valeriya D. Frolova, Barbara Z. Eletskaya, Olga S. Smirnova, Maria Ya. Berzina, Alexandra O. Arnautova, Yulia A. Abramchik, Maria A. Kostromina, Alexey L. Kayushin, Konstantin V. Antonov, Alexander S. Paramonov, Valeria L. Andronova, Georgiy A. Galegov, Roman S. Esipov, Shakhnoz S. Azimova, Anatoly I. Miroshnikov, Irina D. Konstantinova
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-06-01
シリーズ:	Biomolecules
主題:	nucleoside phosphorylases nucleosides ribavirin antiviral activity
オンライン･アクセス:	https://www.mdpi.com/2218-273X/14/7/745
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