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Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlapResearch in context

Summary: Background: Metabolic dysfunction is a major risk factor for neurodegeneration, yet the genetic architecture linking systemic metabolism to Alzheimer's disease (AD) and Parkinson's disease (PD) remains unclear. Methods: We integrated genome-wide association data for 249 circulating metabol...

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Príomhchruthaitheoirí: Sara E. Stinson, Alexey A. Shadrin, Zillur Rahman, Linn Rødevand, Iris J. Broce, Geir Selbæk, Hreinn Stefansson, Jan Haavik, Nadine Parker, Elise Koch, Oleksandr Frei, Kevin S. O'Connell, Olav B. Smeland, Srdjan Djurovic, Anders M. Dale, Dennis van der Meer, Ole A. Andreassen
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Elsevier 2026-05-01
Sraith:EBioMedicine
Ábhair:
Metabolomics
Proglucagon
Genome-wide association study
Cardiometabolic disease
Alzheimer's disease
Parkinson's disease
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2352396426001362
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