A novel cultivation strategy to recover NK cell cytotoxicity
Natural killer cells are emerging as promising “off-the-shelf” effectors for cancer immunotherapy, yet expansion of the NK-92 cell line in batch cultivation leads to rapid loss of cytotoxicity concomitant with lactate accumulation. In this study we developed and validated a two-phase manufacturing s...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2026-04-01
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| coleção: | Frontiers in Bioengineering and Biotechnology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fbioe.2026.1797129/full |
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