Investigator-initiated phase I trial of an oligonucleotide therapeutic targeting long noncoding RNA TUG 1 for recurrent glioblastoma

Abstract Background Glioblastoma (GB) is the most common and aggressive primary malignant brain tumor in adults. To date, no effective treatment has been reported for recurrent GB (rGB). Long noncoding RNA taurine upregulated gene 1 (TUG1), which is highly expressed in GB, resolves the formation of...

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主要な著者:	Shoichi Deguchi, Fumiharu Ohka, Yoshiki Shiba, Junya Yamaguchi, Aya Sato, Keiko Shinjo, Yoshiki Arakawa, Yoshitaka Narita, Yutaka Kondo, Ryuta Saito
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-02-01
シリーズ:	BMC Cancer
主題:	Recurrent glioblastoma TUG1 TUGIASO Long noncoding RNA
オンライン･アクセス:	https://doi.org/10.1186/s12885-025-13623-0
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