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Gut microbiota-derived 4-hydroxyphenylacetic acid from resveratrol supplementation prevents obesity through SIRT1 signaling activation

Resveratrol (RSV), a natural polyphenol, has been suggested to influence glucose and lipid metabolism. However, the underlying molecular mechanism of its action remains largely unknown due to its multiple biological targets and low bioavailability. In this study, we demonstrate that RSV supplementat...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Pan Wang, Ruiqi Wang, Wenting Zhao, Yuanyuan Zhao, Dan Wang, Shuang Zhao, Zhiwen Ge, Yue Ma, Xiaoyan Zhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2025-12-01
Schriftenreihe:Gut Microbes
Schlagworte:
Resveratrol
4-hydroxyphenylacetic acid
gut microbiota
obesity
SIRT1
Online-Zugang:https://www.tandfonline.com/doi/10.1080/19490976.2024.2446391
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