Structures of the human Wilson disease copper transporter ATP7B

Summary: The P-type ATPase ATP7B exports cytosolic copper and plays an essential role in the regulation of cellular copper homeostasis. Mutants of ATP7B cause Wilson disease (WD), an autosomal recessive disorder of copper metabolism. Here, we present cryoelectron microscopy (cryo-EM) structures of h...

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Autors principals:	Guo-Min Yang, Lingyi Xu, Rou-Min Wang, Xin Tao, Zi-Wei Zheng, Shenghai Chang, Demin Ma, Cheng Zhao, Yi Dong, Shan Wu, Jiangtao Guo, Zhi-Ying Wu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-05-01
Col·lecció:	Cell Reports
Matèries:	CP: Molecular biology
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S221112472300428X
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