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Transfixed by transgenics: how pathology assumptions are slowing progress in Alzheimer's disease and related dementia research

Abstract Model organisms of human diseases are invaluable tools for unraveling pathogenic mechanisms, identifying potential targets for drug development, and evaluating the therapeutic efficacy of candidates in preclinical trials. The utility of model organisms hinges upon their ability to faithfull...

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Autore principale: Luciano D'Adamio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Nature 2023-09-01
Serie:EMBO Molecular Medicine
Accesso online:https://doi.org/10.15252/emmm.202318479
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