Glabridin‐Gold(I) Complex as a Novel Immunomodulatory Agent Targeting TrxR and MAPK Pathways for Synergistic Enhancement of Antitumor Immunity

Abstract Metal‐based drugs have been utilized as immunomodulatory agents in combination with cancer immunotherapies to induce tumor immunogenicity. However, the immunosuppressive tumor microenvironment significantly hinders the efficacy of these immunomodulatory agents from promoting antitumor immun...

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Главные авторы: Zhaoran Wang, Meiyu Wang, Qiong Chen, Mengshi Wang, Fuwei Li, Lin Lv, Zhenfan Wen, Zhongren Xu, Yixia Yang, Chunyang Bi, Wukun Liu
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley 2025-11-01
Серии:Advanced Science
Предметы:
Immunomodulatory agent
immunosuppressive microenvironment
metal complex
tumor immunotherapy
Online-ссылка:https://doi.org/10.1002/advs.202504729
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